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Table 1 Mortality rate in LF patients treated with ribavirin [39]

From: Lassa fever: another threat from West Africa

Risk group Treatment onset (days from symptom onset) Mortality rate
No treatment (%) Oral ribavirin (%) Intravenous ribavirin (%)
AST >150 IU All cases 55 14* 19*
Within 6 days 61 20* 5*
After >7 days 52 11* 26*
Viremia >103.6 TCID50 All cases 76 30* 32*
Within 6 days 75 20* 9*
After >7 days 78 40* 47*
Viremia <103.6 TCID50 All cases 28 7* 9*
  1. AST aspartate transaminase, TCID 50 50 % Tissue culture inhibitory dose
  2. * Significantly lower than mortality with no treatment